1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity relevant to bortezomib, a proteasome inhibitor Utilized in the treatment of numerous myeloma. Its synthesis or research is crucial for making sure the purity and protection of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor within the synthesis of abiraterone acetate, a drug Employed in the remedy of prostate most cancers by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-10-one): A essential compound while in the synthesis of imatinib, a drug that targets precise kinds of most cancers, together with Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers such as breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are generally intermediates during the synthesis of gemcitabine, an anti-cancer drug. Their analyze is crucial for optimizing the production process and making sure large purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is made use of to treat breast most cancers, and these intermediates are involved in its creation.
Fulvestrant Intermediates: Fulvestrant is an estrogen receptor antagonist Employed in the cure of breast cancer. Various intermediates assist in the synthesis of the drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-16-nine): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug helpful in dealing with cancers such as ovarian, breast, and lung cancer.
three. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (3R (CAS NO. 136572-09-three): A chemotherapy drug Utilized in the procedure of colorectal most cancers and compact cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is associated with the synthesis of adamantane derivatives, that have numerous purposes, together with antiviral Houses.
Vildagliptin Intermediates: Utilized in the production of vildagliptin, an oral drug for kind two diabetes that inhibits the enzyme DPP-4 CAS NO. 571188-59-5 to control blood sugar concentrations.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is involved with the synthesis of assorted gluconic acid derivatives, which can be Employed in food stuff, pharmaceutical, and industrial apps.
Canagliflozin Intermediate 2: A precursor within the synthesis of canagliflozin, a medication applied to handle form 2 diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).